The story revolves around three roommates, journalist Tashi (Imran Khan), photographer Nitin Berry (Kunaal Roy Kapur) and cartoonist Arup (Vir Das), leading an unkempt and debt-ridden life in a shady apartment in Delhi. Tashis ditzy fiancée, Sonia (Shenaz Treasurywala), is an air hostess who agrees to deliver a package for Vladimir Dragunsky (Kim Bodnia) to Somayajulu (Vijay Raaz), without realizing its contents or that Somayajulu is a gangster. Sonia asks Tashi to deliver the package. Tashi, in turn, asks Nitin to do so. But Nitin is unable to do so as he is suffering from travelers diarrhea. Nitin hands Sonias package to Arup for delivery to Somayajulu, along with a package containing his stool sample for delivery to Nitins doctor. Arup mixes up the two bags. Somayajulu, furious, tortures Vladimir to find his package.